Thegold standard specimenfor diagnosingpertussis (Bordetella pertussis infection)is anasopharyngeal culturebecause:
* B. pertussis colonizes the nasopharynx, making it the best site for detection.
* Aproperly collected nasopharyngeal swab or aspirateincreases diagnostic sensitivity.
* This method is recommended forculture, PCR, or direct fluorescent antibody testing.
Why the Other Options Are Incorrect?
* A. Cough plate- Not commonly used due tolow sensitivity.
* B. Nares culture- Thenares are not a primary sitefor pertussis colonization.
* C. Sputum culture-B. pertussis does not commonly infect the lower respiratory tract.
CBIC Infection Control Reference
APIC confirms thatnasopharyngeal culture is the preferred method for diagnosing pertussis.